Item Type | Name |
Concept
|
Aconitate Hydratase
|
Concept
|
Acylation
|
Concept
|
Age Factors
|
Concept
|
Acetylation
|
Concept
|
Aorta, Thoracic
|
Concept
|
Aged, 80 and over
|
Concept
|
Arteriovenous Malformations
|
Concept
|
Ankle
|
Concept
|
Acetylcholine
|
Concept
|
Acetanilides
|
Concept
|
Acetylcysteine
|
Concept
|
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
|
Concept
|
Aged
|
Concept
|
American Heart Association
|
Concept
|
Amino Acid Oxidoreductases
|
Concept
|
Blood Flow Velocity
|
Concept
|
Blood Platelets
|
Concept
|
Blood Pressure
|
Concept
|
Breast Neoplasms
|
Concept
|
Adenosine Triphosphate
|
Concept
|
Carbazoles
|
Concept
|
Catheterization
|
Concept
|
Hypoxia
|
Concept
|
Anticoagulants
|
Concept
|
Angina Pectoris
|
Concept
|
Aorta
|
Concept
|
Aminoquinolines
|
Concept
|
Aortic Valve
|
Concept
|
Analysis of Variance
|
Concept
|
Arginine
|
Concept
|
Aorta, Abdominal
|
Concept
|
Appetite Depressants
|
Concept
|
Benzamides
|
Concept
|
Carotid Body
|
Concept
|
Atropine
|
Concept
|
Dichloroacetic Acid
|
Concept
|
Dimercaprol
|
Concept
|
Dithionitrobenzoic Acid
|
Concept
|
Biotin
|
Concept
|
Body Temperature
|
Concept
|
Biopsy, Needle
|
Concept
|
Body Weight
|
Concept
|
Calmodulin-Binding Proteins
|
Concept
|
Brachial Artery
|
Concept
|
Carcinoma, Non-Small-Cell Lung
|
Concept
|
Ischemic Attack, Transient
|
Concept
|
Chelating Agents
|
Concept
|
Cholesterol, Dietary
|
Concept
|
Catalase
|
Concept
|
Cell Cycle
|
Concept
|
Citric Acid Cycle
|
Concept
|
Chemoreceptor Cells
|
Concept
|
Chicago
|
Concept
|
Blood Pressure Determination
|
Concept
|
Bradykinin
|
Concept
|
Cardiotonic Agents
|
Concept
|
Cholesterol
|
Concept
|
Cytosol
|
Concept
|
Diabetes Mellitus, Type 2
|
Concept
|
Diet Surveys
|
Concept
|
Dithionite
|
Concept
|
Diarrhea
|
Concept
|
Endarterectomy
|
Concept
|
Cytochrome P-450 Enzyme System
|
Concept
|
Disulfides
|
Concept
|
Dithiothreitol
|
Concept
|
Cause of Death
|
Concept
|
Echocardiography
|
Concept
|
Educational Status
|
Concept
|
Glutathione Reductase
|
Concept
|
Health Surveys
|
Concept
|
Clitoris
|
Concept
|
Factor VIII
|
Concept
|
Mass Screening
|
Concept
|
Depression
|
Concept
|
Cross-Sectional Studies
|
Concept
|
Electron Transport Complex IV
|
Concept
|
Double-Blind Method
|
Concept
|
Fluoxetine
|
Concept
|
Fatty Acids, Nonesterified
|
Concept
|
Fibrinogen
|
Concept
|
Enzyme Activation
|
Concept
|
Methyltransferases
|
Concept
|
Fasting
|
Concept
|
Fatty Acids
|
Concept
|
Fatty Acids, Unsaturated
|
Concept
|
Feasibility Studies
|
Concept
|
DNA (Cytosine-5-)-Methyltransferases
|
Concept
|
Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)
|
Concept
|
Cyclic GMP
|
Concept
|
Cardiac Catheterization
|
Concept
|
Dose-Response Relationship, Drug
|
Concept
|
Dyspnea
|
Concept
|
Liposomes
|
Concept
|
Heptanoic Acids
|
Concept
|
Herbicides
|
Concept
|
Hexokinase
|
Concept
|
Infusions, Intravenous
|
Concept
|
Gastroesophageal Reflux
|
Concept
|
Guanylate Cyclase
|
Concept
|
Headache
|
Concept
|
Macrophages
|
Concept
|
Mammary Arteries
|
Concept
|
Ketanserin
|
Concept
|
Hirudins
|
Concept
|
Metformin
|
Concept
|
Phosphatidylcholines
|
Concept
|
Pilot Projects
|
Concept
|
Mice, Transgenic
|
Concept
|
Minnesota
|
Concept
|
Mitosis
|
Concept
|
Pneumonia, Viral
|
Concept
|
Meclofenamic Acid
|
Concept
|
Exanthema
|
Concept
|
Organ Size
|
Concept
|
NADP
|
Concept
|
Glycolysis
|
Concept
|
Oxidative Phosphorylation
|
Concept
|
Pancreatic Elastase
|
Concept
|
Middle Aged
|
Concept
|
Random Allocation
|
Concept
|
Health Policy
|
Concept
|
Heartburn
|
Concept
|
HeLa Cells
|
Concept
|
Herpes Simplex
|
Concept
|
Pergolide
|
Concept
|
Neutrophils
|
Concept
|
Phagocytosis
|
Concept
|
Oxidoreductases
|
Concept
|
Cholesterol, HDL
|
Concept
|
Lung Neoplasms
|
Concept
|
Safety
|
Concept
|
Oxygen Inhalation Therapy
|
Concept
|
Peptide Elongation Factors
|
Concept
|
Methylene Blue
|
Concept
|
Mitochondria, Heart
|
Concept
|
Phthalimides
|
Concept
|
Phospholipases
|
Concept
|
Phosphorylation
|
Concept
|
NAD
|
Concept
|
Feeding Behavior
|
Concept
|
Porphyrins
|
Concept
|
Sulfones
|
Concept
|
Taste
|
Concept
|
Phycoerythrin
|
Concept
|
Propionates
|
Concept
|
Thymoma
|
Concept
|
Protein Binding
|
Concept
|
Protein Processing, Post-Translational
|
Concept
|
Pulmonary Gas Exchange
|
Concept
|
Triterpenes
|
Concept
|
Glyburide
|
Concept
|
Glomerular Mesangium
|
Concept
|
Regression Analysis
|
Concept
|
Renal Circulation
|
Concept
|
Referral and Consultation
|
Concept
|
Registries
|
Concept
|
Prostaglandin-Endoperoxide Synthases
|
Concept
|
Restaurants
|
Concept
|
Risk Factors
|
Concept
|
Vasomotor System
|
Concept
|
Protein Kinases
|
Concept
|
Serotonin Antagonists
|
Concept
|
Pyruvate Kinase
|
Concept
|
Quality of Life
|
Concept
|
von Willebrand Factor
|
Concept
|
Xanthine Oxidase
|
Concept
|
Somatostatin
|
Concept
|
Species Specificity
|
Concept
|
Rotenone
|
Concept
|
Cohort Studies
|
Concept
|
Renal Artery
|
Concept
|
Scleroderma, Systemic
|
Concept
|
Smoking
|
Concept
|
Sarcoidosis
|
Concept
|
Serotonin
|
Concept
|
Sensitivity and Specificity
|
Concept
|
Swine
|
Concept
|
Thrombin
|
Concept
|
Silver
|
Concept
|
Societies, Medical
|
Concept
|
Humans
|
Concept
|
Hypercapnia
|
Concept
|
Tomography, Emission-Computed, Single-Photon
|
Concept
|
Incidence
|
Concept
|
Linear Models
|
Concept
|
Single-Blind Method
|
Concept
|
Benzoquinones
|
Concept
|
Tomography, X-Ray Computed
|
Concept
|
Transcription, Genetic
|
Concept
|
Superoxides
|
Concept
|
Training Support
|
Concept
|
Intracellular Membranes
|
Concept
|
Thionucleotides
|
Concept
|
Thrombin Time
|
Concept
|
Ultrasonography
|
Concept
|
United States
|
Concept
|
Stroke Volume
|
Concept
|
Superoxide Dismutase
|
Concept
|
Oxidants
|
Concept
|
Ubiquinone
|
Concept
|
Ion Transport
|
Concept
|
Thiophenes
|
Concept
|
3',5'-Cyclic-GMP Phosphodiesterases
|
Concept
|
Sex Distribution
|
Concept
|
Myocardial Stunning
|
Concept
|
Kidney
|
Concept
|
Echocardiography, Doppler
|
Concept
|
Transduction, Genetic
|
Concept
|
Hyperoxia
|
Concept
|
Proportional Hazards Models
|
Concept
|
Randomized Controlled Trials as Topic
|
Concept
|
Risk Assessment
|
Concept
|
Radiopharmaceuticals
|
Concept
|
Oleic Acid
|
Concept
|
rho GTP-Binding Proteins
|
Concept
|
rhoB GTP-Binding Protein
|
Concept
|
S Phase
|
Concept
|
Guanosine 5'-O-(3-Thiotriphosphate)
|
Concept
|
Ventricular Function, Left
|
Concept
|
4-Aminopyridine
|
Concept
|
Up-Regulation
|
Concept
|
5,8,11,14-Eicosatetraynoic Acid
|
Concept
|
Extracorporeal Membrane Oxygenation
|
Concept
|
Prevalence
|
Concept
|
G1 Phase
|
Concept
|
Cardiopulmonary Resuscitation
|
Concept
|
Fatty Acids, Omega-3
|
Concept
|
Ion Channel Gating
|
Concept
|
Antigens, CD
|
Concept
|
Lupus Erythematosus, Systemic
|
Concept
|
Mitochondria
|
Concept
|
Mitochondria, Muscle
|
Concept
|
Infusion Pumps, Implantable
|
Concept
|
Chi-Square Distribution
|
Concept
|
Comorbidity
|
Concept
|
N-Acetylgalactosaminyltransferases
|
Concept
|
Proto-Oncogene Proteins c-myc
|
Concept
|
Tacrolimus
|
Concept
|
Case-Control Studies
|
Concept
|
Age Distribution
|
Concept
|
Time Management
|
Concept
|
Treatment Outcome
|
Concept
|
NADH Dehydrogenase
|
Concept
|
Panic Disorder
|
Concept
|
Arachidonic Acid
|
Concept
|
Cyclooxygenase Inhibitors
|
Concept
|
Tachycardia, Ventricular
|
Concept
|
Apoptosis
|
Concept
|
Mice, Knockout
|
Concept
|
Videoconferencing
|
Concept
|
Charybdotoxin
|
Concept
|
Telomerase
|
Concept
|
omega-N-Methylarginine
|
Concept
|
Cytochrome P-450 CYP2E1
|
Concept
|
Inhibitor of Apoptosis Proteins
|
Concept
|
Simvastatin
|
Concept
|
Dietary Sucrose
|
Concept
|
Bone Morphogenetic Protein Receptors, Type II
|
Concept
|
Tetraethylammonium
|
Concept
|
Calcium Signaling
|
Concept
|
Venous Thrombosis
|
Concept
|
Cross-Over Studies
|
Concept
|
SOXF Transcription Factors
|
Concept
|
GTP Phosphohydrolases
|
Concept
|
Sirtuin 3
|
Concept
|
Fatal Outcome
|
Concept
|
Cyclic GMP-Dependent Protein Kinases
|
Concept
|
Biomimetics
|
Concept
|
MAP Kinase Kinase 4
|
Concept
|
Positron-Emission Tomography
|
Concept
|
Proteomics
|
Concept
|
Proteasome Endopeptidase Complex
|
Concept
|
Ryanodine Receptor Calcium Release Channel
|
Concept
|
Sexual Dysfunctions, Psychological
|
Concept
|
5' Untranslated Regions
|
Concept
|
3' Untranslated Regions
|
Concept
|
rhoA GTP-Binding Protein
|
Concept
|
Cell-Matrix Junctions
|
Concept
|
Thrombospondins
|
Concept
|
Prenatal Exposure Delayed Effects
|
Concept
|
Promoter Regions, Genetic
|
Concept
|
Pulmonary Artery
|
Concept
|
Surveys and Questionnaires
|
Concept
|
Scorpion Venoms
|
Concept
|
Serine
|
Concept
|
Serum Albumin
|
Concept
|
Severity of Illness Index
|
Concept
|
Mechanotransduction, Cellular
|
Concept
|
Substance P
|
Concept
|
Electron Transport Complex I
|
Concept
|
Sulfonamides
|
Concept
|
Biomedical Research
|
Concept
|
Dioxygenases
|
Concept
|
Cytokine Receptor gp130
|
Concept
|
Proteolysis
|
Concept
|
Nitric Oxide Synthase Type II
|
Concept
|
PPAR alpha
|
Concept
|
Staphylococcus aureus
|
Concept
|
Blotting, Western
|
Concept
|
Down-Regulation
|
Concept
|
STAT2 Transcription Factor
|
Concept
|
HIV Infections
|
Concept
|
Multivariate Analysis
|
Concept
|
Logistic Models
|
Concept
|
Survival Analysis
|
Concept
|
CDC2 Protein Kinase
|
Concept
|
Tetraethylammonium Compounds
|
Concept
|
Thallium
|
Concept
|
Thyroid Neoplasms
|
Concept
|
Cell Death
|
Concept
|
Transfection
|
Concept
|
von Willebrand Diseases
|
Concept
|
8,11,14-Eicosatrienoic Acid
|
Concept
|
Reproducibility of Results
|
Concept
|
Patient Satisfaction
|
Concept
|
Myocardial Reperfusion Injury
|
Concept
|
Survival Rate
|
Concept
|
Odds Ratio
|
Concept
|
Magnetic Resonance Imaging, Cine
|
Concept
|
Telemedicine
|
Concept
|
DNA Methylation
|
Concept
|
NADPH Oxidases
|
Concept
|
Echocardiography, Transesophageal
|
Concept
|
Nitric Oxide Synthase
|
Concept
|
Gadolinium DTPA
|
Concept
|
Polypyrimidine Tract-Binding Protein
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
Concept
|
Cell Cycle Checkpoints
|
Concept
|
Transcriptome
|
Concept
|
Genome-Wide Association Study
|
Concept
|
X-Ray Microtomography
|
Concept
|
AMP-Activated Protein Kinases
|
Concept
|
Secondary Prevention
|
Concept
|
Dynamins
|
Concept
|
Heterogeneous-Nuclear Ribonucleoproteins
|
Concept
|
RNA, Small Interfering
|
Concept
|
Pandemics
|
Concept
|
Ribosomal Protein S6 Kinases, 70-kDa
|
Concept
|
Vascular Endothelial Growth Factor A
|
Concept
|
Cell Line, Tumor
|
Concept
|
Nitric Oxide Synthase Type III
|
Concept
|
Quinazolinones
|
Concept
|
Kaplan-Meier Estimate
|
Concept
|
Latent TGF-beta Binding Proteins
|
Concept
|
Nicotinamide Phosphoribosyltransferase
|
Concept
|
rho-Associated Kinases
|
Concept
|
Cyclic Nucleotide Phosphodiesterases, Type 5
|
Concept
|
Antibodies, Antinuclear
|
Concept
|
Coronary Artery Bypass
|
Concept
|
Benzenesulfonates
|
Concept
|
Calcium
|
Concept
|
Clinical Trials as Topic
|
Concept
|
Coronary Vessels
|
Concept
|
Disease Models, Animal
|
Concept
|
Electron Transport
|
Concept
|
Factor VII
|
Concept
|
Fetal Hypoxia
|
Concept
|
Follow-Up Studies
|
Concept
|
Food Preferences
|
Concept
|
Glucose
|
Concept
|
Guanosine Diphosphate
|
Concept
|
Heart Rate
|
Concept
|
Erectile Dysfunction
|
Concept
|
Kinetics
|
Concept
|
Longitudinal Studies
|
Concept
|
Lymphocytes
|
Concept
|
Magnetic Resonance Imaging
|
Concept
|
NADH, NADPH Oxidoreductases
|
Concept
|
NADPH Dehydrogenase
|
Concept
|
Norepinephrine
|
Concept
|
Phosphoric Diester Hydrolases
|
Concept
|
Predictive Value of Tests
|
Concept
|
Prospective Studies
|
Concept
|
Pyruvate Dehydrogenase Complex
|
Concept
|
Recombinant Fusion Proteins
|
Concept
|
Respiration, Artificial
|
Concept
|
Retrospective Studies
|
Concept
|
Syncope
|
Concept
|
Systole
|
Concept
|
Vitamin A
|
Concept
|
Wisconsin
|
Concept
|
World Health Organization
|
Concept
|
Hypertriglyceridemia
|
Concept
|
Signal Transduction
|
Concept
|
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
|
Concept
|
Okadaic Acid
|
Concept
|
p38 Mitogen-Activated Protein Kinases
|
Concept
|
G-Protein-Coupled Receptor Kinase 2
|
Concept
|
Lung Injury
|
Concept
|
Young Adult
|
Academic Article
|
Diagnosis of pulmonary vein varix by transesophageal echocardiography.
|
Academic Article
|
Superoxide dismutase: an antireductant enzyme?
|
Academic Article
|
Opposing effects of oxidants and antioxidants on K+ channel activity and tone in rat vascular tissue.
|
Academic Article
|
Postischemic oxygen radical production varies with duration of ischemia.
|
Academic Article
|
The non specificity of specific nitric oxide synthase inhibitors.
|
Academic Article
|
Differential distribution of electrophysiologically distinct myocytes in conduit and resistance arteries determines their response to nitric oxide and hypoxia.
|
Academic Article
|
Measurement of nitric oxide in biological models.
|
Academic Article
|
Nebulized nitric oxide/nucleophile adduct reduces chronic pulmonary hypertension.
|
Academic Article
|
Chronic infusion of nitric oxide in experimental pulmonary hypertension: pulmonary pressure-flow analysis.
|
Academic Article
|
A placebo-controlled trial of prostacyclin in acute respiratory failure in COPD.
|
Academic Article
|
Oxygen-induced constriction of rabbit ductus arteriosus occurs via inhibition of a 4-aminopyridine-, voltage-sensitive potassium channel.
|
Academic Article
|
Activation of the cGMP-dependent protein kinase mimics the stimulatory effect of nitric oxide and cGMP on calcium-gated potassium channels.
|
Academic Article
|
Oxygen causes fetal pulmonary vasodilation through activation of a calcium-dependent potassium channel.
|
Academic Article
|
Ventilation-induced pulmonary vasodilation at birth is modulated by potassium channel activity.
|
Academic Article
|
Acute hypoxic pulmonary vasoconstriction: a model of oxygen sensing.
|
Academic Article
|
The somatostatin analog angiopeptin does not reduce chronic hypoxic pulmonary hypertension in rats.
|
Academic Article
|
Origins of breath nitric oxide in humans.
|
Academic Article
|
Potassium channel diversity in vascular smooth muscle cells.
|
Academic Article
|
Sildenafil: from the bench to the bedside.
|
Academic Article
|
In memoriam : Francis X. Witkowski.
|
Academic Article
|
Alterations in a redox oxygen sensing mechanism in chronic hypoxia.
|
Academic Article
|
Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes.
|
Academic Article
|
Pulmonary vasoconstriction, oxygen sensing, and the role of ion channels: Thomas A. Neff lecture.
|
Academic Article
|
Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv1.5.
|
Academic Article
|
Redox control of oxygen sensing in the rabbit ductus arteriosus.
|
Academic Article
|
GTP (gammaS) and GDP (betaS) as electron donors: new wine in old bottles.
|
Academic Article
|
Dexfenfluramine elevates systemic blood pressure by inhibiting potassium currents in vascular smooth muscle cells.
|
Academic Article
|
Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels.
|
Academic Article
|
O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase.
|
Academic Article
|
Triple-bonded unsaturated fatty acids are redox active compounds.
|
Academic Article
|
Primary pulmonary hypertension: a vascular biology and translational research "Work in progress".
|
Academic Article
|
Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models.
|
Academic Article
|
Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels.
|
Academic Article
|
Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension.
|
Academic Article
|
Canadian Cardiovascular Society and Canadian Thoracic Society position statement on pulmonary arterial hypertension.
|
Academic Article
|
An evidence-based approach to the management of pulmonary arterial hypertension.
|
Academic Article
|
Measurement of endothelial cytosolic calcium concentration and nitric oxide production reveals discrete mechanisms of endothelium-dependent pulmonary vasodilatation.
|
Academic Article
|
Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization.
|
Academic Article
|
The NO - K+ channel axis in pulmonary arterial hypertension. Activation by experimental oral therapies.
|
Academic Article
|
An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
|
Academic Article
|
Images in cardiovascular medicine. Untreated 37-year-old homozygous familial hypercholesterolemic smoker.
|
Academic Article
|
Association of education with dietary intake among young adults in the bi-ethnic Coronary Artery Risk Development in Young Adults (CARDIA) cohort.
|
Academic Article
|
Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension.
|
Academic Article
|
Enhanced chemiluminescence as a measure of oxygen-derived free radical generation during ischemia and reperfusion.
|
Academic Article
|
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted.
|
Academic Article
|
Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells.
|
Academic Article
|
Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus.
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Academic Article
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ZK 36-374, a stable analog of prostacyclin, prevents acute hypoxic pulmonary hypertension in the dog.
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Survival in pulmonary arterial hypertension: a reappraisal of the NIH risk stratification equation.
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The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle.
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A dosing/cross-development study of the multikinase inhibitor sorafenib in patients with pulmonary arterial hypertension.
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Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction.
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Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies.
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Diagnosis and management of pulmonary hypertension in systemic sclerosis.
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A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.
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Academic Article
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Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure.
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Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility.
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Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association.
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Developmental absence of the O2 sensitivity of L-type calcium channels in preterm ductus arteriosus smooth muscle cells impairs O2 constriction contributing to patent ductus arteriosus.
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Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer.
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Myocardial damage in patients with sarcoidosis and preserved left ventricular systolic function: an observational study.
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Oxygen radicals and antioxidant enzymes alter pulmonary vascular reactivity in the rat lung.
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Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle.
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Lung ¹8F-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring of pulmonary arterial hypertension.
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Academic Article
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Hypoxic pulmonary vasoconstriction is unaltered by creatine depletion induced by dietary beta-guanidino propionic acid.
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Association of serum creatinine with abnormal hemodynamics and mortality in pulmonary arterial hypertension.
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Academic Article
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Chronic primary and secondary thromboembolic pulmonary hypertension.
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Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.
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The effects of substance P on the preconstricted pulmonary vasculature of the anesthetized dog.
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Aetiology and management of male erectile dysfunction and female sexual dysfunction in patients with cardiovascular disease.
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Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor.
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Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats.
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Value of exercise treadmill testing in the risk stratification of patients with pulmonary hypertension.
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Five-year follow-up of a multicenter, double-blind randomized clinical trial of laparoscopic Nissen vs anterior 90 degrees partial fundoplication.
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The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.
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Academic Article
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Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
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Superoxide reduction of a disulfide: a model of intracellular redox modulation?
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Exercise thallium testing in ventricular preexcitation.
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Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase.
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Academic Article
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Effect of graded hypoxia on the induction and function of inducible nitric oxide synthase in rat mesangial cells.
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Academic Article
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Redox status in the control of pulmonary vascular tone.
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Academic Article
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Dithionite increases radical formation and decreases vasoconstriction in the lung. Evidence that dithionite does not mimic alveolar hypoxia.
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Effects of dietary fish oil on lung phospholipid fatty acid composition and intrinsic pulmonary vascular reactivity.
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Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study.
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A redox-based O2 sensor in rat pulmonary vasculature.
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Chronic hypoxic pulmonary hypertension. Is thrombin involved?
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Simultaneous measurement of O2 radicals and pulmonary vascular reactivity in rat lung.
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The mitochondrion as a Swiss army knife: implications for cardiovascular disease.
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Diversity of phenotype and function of vascular smooth muscle cells.
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Effect of dietary fish oil on lung lipid profile and hypoxic pulmonary hypertension.
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Late gadolinium enhancement cardiovascular magnetic resonance predicts clinical worsening in patients with pulmonary hypertension.
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Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction.
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NG-monomethyl-L-arginine causes nitric oxide synthesis in isolated arterial rings: trouble in paradise.
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The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels.
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A role for potassium channels in smooth muscle cells and platelets in the etiology of primary pulmonary hypertension.
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The measurement of NO in biological systems using chemiluminescence.
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Academic Article
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Potassium channels regulate tone in rat pulmonary veins.
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Academic Article
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O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor.
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Usefulness of mean aortic valve gradient and left ventricular diastolic filling pattern for distinguishing symptomatic from asymptomatic patients.
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Academic Article
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Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction.
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Academic Article
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ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association.
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A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension.
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H2O2 injury causes Ca(2+)-dependent and -independent hydrolysis of phosphatidylcholine in alveolar epithelial cells.
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PGC1a-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension.
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Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF(121) (AdVEGF121) versus maximum medical treatment.
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Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension.
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FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate.
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Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus.
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GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension.
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Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension.
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SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress.
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Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension.
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Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
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Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide.
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Pulmonary arterial hypertension: pathogenesis and clinical management.
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Disproportionate Right Ventricular Dysfunction and Poor Survival in Group 3 Pulmonary Hypertension.
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Association of dietary fish and n-3 fatty acid intake with hemostatic factors in the coronary artery risk development in young adults (CARDIA) study.
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Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertension.
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The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease.
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The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure.
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Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension.
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Accelerated disulfide reduction with polyunsaturated fatty acids: a mechanism of ionic channel modulation?
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Mitochondrial fission and fusion in human diseases.
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Pulmonary hypertension begets pulmonary hypertension: mutually reinforcing roles for haemodynamics, inflammation, and cancer-like phenotypes.
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Increasing Incidence and Prevalence of World Health Organization Groups 1 to 4 Pulmonary Hypertension: A Population-Based Cohort Study in Ontario, Canada.
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A Step Closer to Understanding How Riociguat Results in Remodelling of the Right Ventricle in Chronic Thromboembolic Pulmonary Hypertension.
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Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat.
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Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury.
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Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension.
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Differentiating COVID-19 Pneumonia From Acute Respiratory Distress Syndrome and High Altitude Pulmonary Edema: Therapeutic Implications.
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Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension.
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Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling.
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Academic Article
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Scientist on the Spot: Exploring the cause and cure for pulmonary arterial hypertension.
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Corrigendum to: Scientist on the spot: Exploring the cause and cure for pulmonary arterial hypertension.
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Academic Article
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The molecular mechanisms of oxygen-sensing in human ductus arteriosus smooth muscle cells: A comprehensive transcriptome profile reveals a central role for mitochondria.
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Academic Article
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Carvedilol for Treatment of Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
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Diagnosis and Treatment of Right Heart Failure in Pulmonary Vascular Diseases: A National Heart, Lung, and Blood Institute Workshop.
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Mitochondrial iron-sulfur clusters: Structure, function, and an emerging role in vascular biology.
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Anomalous Right Coronary Artery Arising From Distal Left Circumflex Artery.
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Academic Article
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Acquired disorders of mitochondrial metabolism and dynamics in pulmonary arterial hypertension.
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Concept
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Imatinib Mesylate
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Concept
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Sildenafil Citrate
|
Concept
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Ranolazine
|
Concept
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A549 Cells
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Concept
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Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
|
Concept
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Soluble Guanylyl Cyclase
|
Concept
|
Betacoronavirus
|
Concept
|
NADPH Oxidase 2
|
Concept
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DNA (Cytosine-5-)-Methyltransferase 1
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Concept
|
Hernias, Diaphragmatic, Congenital
|
Concept
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Familial Primary Pulmonary Hypertension
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Concept
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ErbB Receptors
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Grant
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O2 sensing in the human and rabbit ductus arteriosus.
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Academic Article
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The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases.
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